
The Grand National will be reduced to a maximum of 34 runners from 40 as part of measures designed to improve safety.
One horse died in this year's race, which was delayed by 14 minutes after a protest by animal rights activists.
Organisers plan an earlier race time at Aintree to provide safer ground for runners, and a shorter run to the first fence to slow horses down early on.
The introduction of a standing start and further veterinary checks are among other changes.
There had been some calls for the line-up to be reduced to 30 runners, but Aintree clerk of the course Sulekha Varma said that could be counter-productive.
"We know from research papers and internal analysis of jump races that there is a direct correlation between the number of runners and the risk of falling, unseating or being brought down," she said.
"However, we also must consider that reducing the field size by too great a number could create a faster race and have an adverse impact in terms of safety."
There were three equine fatalities across the three-day National meeting in April, with protesters from Animal Rising attempting to halt the big race itself, although racing chiefs say the changes were not prompted by the protests.
Merseyside Police said 118 people were arrested over the disruption and its investigation is ongoing although no-one has yet been charged six months on.
Emma Slawinski, director of policy at the RSPCA, welcomed the new steps at Aintree, but said more could be done.
"We look forward to seeing this announcement pave the way for further changes," she added.
Nevin Truesdale, chief executive of Aintree owners the Jockey Club, said the changes were part of the organisation's "relentless focus on welfare".
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